Application

Goat Anti-Guinea Pig IgG Antibody, HRP conjugate has been used in immunoblot analysis and enzyme-linked immunosorbent assay (ELISA) (1:2000).

Biochem/physiol Actions

Immunoglobulin G (IgG) initiates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays an essential role in antibody-dependent cell-mediated cytotoxicity (ADCC). Maternal IgG is transferred to the fetus through the placenta that is crucial for protecting newborns against infectious diseases. Levels of IgG in severe acute respiratory syndrome coronavirus (SARS‐CoV)‐2 infected patients can be used as a potential tool to evaluate the severity and prognosis of coronavirus disease 2019 (COVID‐19).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Immunoglobulin G (IgG) is the most common type of antibody in the human serum. It exists in four isotypes IgG1, IgG2, IgG3, and IgG4. IgG is produced by the B cells. IgG structure contains four polypeptide chains with two identical heavy (H) chains and two identical λ light (L) chains. These chains are inter-linked by disulfide bonds.

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